Potential of orange juice in the fight against inflammation, oxidative stress: study
Washington [US], Oct. 24 (ANI): A recent study indicates that orange juice has the potential to help fight inflammation and oxidative stress in adults.
The results of the study were published in the journal “Advances in Nutrition”. Although of limited scope, the study indicates that consuming 100% orange juice significantly reduces interleukin 6, a well-established marker of inflammation, in both healthy and high-risk subjects. adults.
Two additional markers of inflammatory and oxidative stress were also reduced; however, the results did not quite reach statistical significance.
The results of this study, which was funded by an unrestricted grant from the Florida Department of Citrus, align with a previously published FDOC-funded review that reported the beneficial effects of hesperidin, the major bioactive compound found in oranges and 100 percent orange juice, on the reduction of certain markers of inflammation and oxidative stress.
Chronic inflammation can play a key role in the onset or progression of certain chronic diseases, including heart disease and diabetes.
“We know that 100% orange juice contains a number of nutrients, like vitamin C, as well as beneficial bioactive compounds that have the potential to reduce inflammation and oxidative stress,” said Gail Rampersaud, Florida Department of Citrus Registered Dietitian.
“This review tells us that some studies find benefits with 100% orange juice, but we need more data and large, well-designed studies to draw more definitive conclusions. This review is particularly useful because we and we are planning further research related to orange juice, ”Rampersaud added.
The review looked at published studies regarding 100% orange juice and markers of inflammation and oxidative stress. The review was conducted by the Think Healthy Group and researchers from Tufts University and George Mason University.
The analysis consisted of three parts: a qualitative review of the scope of 21 studies involving a total of 307 healthy adults and 327 adults at risk for disease; a systematic review of a subset of 16 studies that measured the six most reported biomarkers related to inflammation and oxidative stress in the body; and 10 studies that had sufficient data to conduct a meta-analysis. The researchers also looked at the overall quality and potential bias of the studies.
General and systematic reviews revealed that in general 100% orange juice had either beneficial or no (no adverse effects) effects on oxidative stress or inflammation.
The researchers cautioned that the studies included a relatively small number of subjects, had low weight of evidence, and were at moderate risk of bias; therefore, overall results should be interpreted with caution. (ANI)